In Layout XL, I find the annotation browser to be more of a hindrance than anything as it's continuously highlighting nets, dimming the layout etc, regarding things that I don't care about. Quite often it'll regard things as errors that aren't errors at all because it doesn't have the same knowledge of the layout as the LVS program and misinterprets things.
I'd love to be able to turn it off completely but I can't find a way.